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MLL4 binds TET3.
Becht DC, Mohid SA, Lee JE, Zandian M, Benz C, Biswas S, Sinha VK, Ivarsson Y, Ge K, Zhang Y, Kutateladze TG. Becht DC, et al. Structure. 2024 Jun 6;32(6):706-714.e3. doi: 10.1016/j.str.2024.03.005. Epub 2024 Apr 4. Structure. 2024. PMID: 38579707
Dusquetide modulates innate immune response through binding to p62.
Zhang Y, Towers CG, Singh UK, Liu J, Håkansson M, Logan DT, Donini O, Kutateladze TG. Zhang Y, et al. Structure. 2022 Aug 4;30(8):1055-1061.e7. doi: 10.1016/j.str.2022.05.003. Epub 2022 May 30. Structure. 2022. PMID: 35640615 Free PMC article.
ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Zhang Y, Xie G, Lee JE, Zandian M, Sudarshan D, Estavoyer B, Benz C, Viita T, Asgaritarghi G, Lachance C, Messmer C, Simonetti L, Sinha VK, Lambert JP, Chen YW, Wang SP, Ivarsson Y, Affar EB, Côté J, Ge K, Kutateladze TG. Zhang Y, et al. Nat Commun. 2024 Jun 7;15(1):4883. doi: 10.1038/s41467-024-49391-x. Nat Commun. 2024. PMID: 38849395 Free PMC article.