R01 AG027317/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2006	1
2007	1
2008	1
2009	3
2010	3
2012	1
2013	1
2014	2
2015	3
2016	2
2018	1
2019	1
2020	1
2021	1
2022	2
2024	1

1

Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia.

Zhu X, Schrader JM, Irizarry BA, Smith SO, Van Nostrand WE. Zhu X, et al. Biomedicines. 2022 Nov 19;10(11):2982. doi: 10.3390/biomedicines10112982. Biomedicines. 2022. PMID: 36428550 Free PMC article.

2

Insights into Cerebral Amyloid Angiopathy Type 1 and Type 2 from Comparisons of the Fibrillar Assembly and Stability of the Aβ40-Iowa and Aβ40-Dutch Peptides.

Rajpoot J, Crooks EJ, Irizarry BA, Amundson A, Van Nostrand WE, Smith SO. Rajpoot J, et al. Biochemistry. 2022 Jun 21;61(12):1181-1198. doi: 10.1021/acs.biochem.1c00781. Epub 2022 Jun 6. Biochemistry. 2022. PMID: 35666749 Free PMC article.

3

Mechanism of Nucleated Conformational Conversion of Aβ42.

Fu Z, Aucoin D, Davis J, Van Nostrand WE, Smith SO. Fu Z, et al. Biochemistry. 2015 Jul 14;54(27):4197-207. doi: 10.1021/acs.biochem.5b00467. Epub 2015 Jun 26. Biochemistry. 2015. PMID: 26069943

4

Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils.

Irizarry BA, Davis J, Zhu X, Boon BDC, Rozemuller AJM, Van Nostrand WE, Smith SO. Irizarry BA, et al. J Biol Chem. 2021 Nov;297(5):101259. doi: 10.1016/j.jbc.2021.101259. Epub 2021 Sep 29. J Biol Chem. 2021. PMID: 34599967 Free PMC article.

5

A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy.

Davis J, Xu F, Hatfield J, Lee H, Hoos MD, Popescu D, Crooks E, Kim R, Smith SO, Robinson JK, Benveniste H, Van Nostrand WE. Davis J, et al. Am J Pathol. 2018 Dec;188(12):2877-2889. doi: 10.1016/j.ajpath.2018.07.030. Epub 2018 Nov 13. Am J Pathol. 2018. PMID: 30446159 Free PMC article.

6

What is the role of amyloid precursor protein dimerization?

Khalifa NB, Van Hees J, Tasiaux B, Huysseune S, Smith SO, Constantinescu SN, Octave JN, Kienlen-Campard P. Khalifa NB, et al. Cell Adh Migr. 2010 Apr-Jun;4(2):268-72. doi: 10.4161/cam.4.2.11476. Epub 2010 Apr 11. Cell Adh Migr. 2010. PMID: 20400860 Free PMC article.

7

N-terminal domain of myelin basic protein inhibits amyloid beta-protein fibril assembly.

Liao MC, Hoos MD, Aucoin D, Ahmed M, Davis J, Smith SO, Van Nostrand WE. Liao MC, et al. J Biol Chem. 2010 Nov 12;285(46):35590-8. doi: 10.1074/jbc.M110.169599. Epub 2010 Aug 31. J Biol Chem. 2010. PMID: 20807757 Free PMC article.

8

Degradation of amyloid beta protein by purified myelin basic protein.

Liao MC, Ahmed M, Smith SO, Van Nostrand WE. Liao MC, et al. J Biol Chem. 2009 Oct 16;284(42):28917-25. doi: 10.1074/jbc.M109.050856. Epub 2009 Aug 19. J Biol Chem. 2009. PMID: 19692707 Free PMC article.

9

Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice.

Xu F, Kotarba AE, Ou-Yang MH, Fu Z, Davis J, Smith SO, Van Nostrand WE. Xu F, et al. J Biol Chem. 2014 Jun 20;289(25):17895-908. doi: 10.1074/jbc.M113.536565. Epub 2014 May 14. J Biol Chem. 2014. PMID: 24828504 Free PMC article.

10

An electrostatic cluster guides Aβ40 fibril formation in sporadic and Dutch-type cerebral amyloid angiopathy.

Fu Z, Crooks EJ, Irizarry BA, Zhu X, Chowdhury S, Van Nostrand WE, Smith SO. Fu Z, et al. J Struct Biol. 2024 Jun;216(2):108092. doi: 10.1016/j.jsb.2024.108092. Epub 2024 Apr 13. J Struct Biol. 2024. PMID: 38615725 Free PMC article.

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