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Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.
Cell Stem Cell. 2007 Jun 7;1(1):113-126. doi: 10.1016/j.stem.2007.03.002.
Cell Stem Cell. 2007.
PMID: 18371340
Free PMC article.
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.
Ruzankina Y, Schoppy DW, Asare A, Clark CE, Vonderheide RH, Brown EJ.
Ruzankina Y, et al.
Nat Genet. 2009 Oct;41(10):1144-9. doi: 10.1038/ng.441. Epub 2009 Aug 30.
Nat Genet. 2009.
PMID: 19718024
Free PMC article.
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Removing all obstacles: a critical role for p53 in promoting tissue renewal.
Schoppy DW, Ruzankina Y, Brown EJ.
Schoppy DW, et al.
Cell Cycle. 2010 Apr 1;9(7):1313-9. doi: 10.4161/cc.9.7.11194. Epub 2010 Apr 1.
Cell Cycle. 2010.
PMID: 20234190
Free PMC article.
Review.
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