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AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin.
Penchala SC, Connelly S, Wang Y, Park MS, Zhao L, Baranczak A, Rappley I, Vogel H, Liedtke M, Witteles RM, Powers ET, Reixach N, Chan WK, Wilson IA, Kelly JW, Graef IA, Alhamadsheh MM. Penchala SC, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9992-7. doi: 10.1073/pnas.1300761110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716704 Free PMC article.
Mutasynthesis of a potent anticancer sibiromycin analogue.
Yonemoto IT, Li W, Khullar A, Reixach N, Gerratana B. Yonemoto IT, et al. ACS Chem Biol. 2012 Jun 15;7(6):973-7. doi: 10.1021/cb200544u. Epub 2012 Mar 23. ACS Chem Biol. 2012. PMID: 22390171 Free PMC article.