R01 AG046929/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2014	1
2015	3
2016	4
2017	3
2018	1
2019	5
2020	3
2021	2
2022	2
2023	2
2024	1

1

Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance.

Singh N, Das B, Zhou J, Hu X, Yan R. Singh N, et al. Sci Adv. 2022 Jul 22;8(29):eabo3610. doi: 10.1126/sciadv.abo3610. Epub 2022 Jul 20. Sci Adv. 2022. PMID: 35857844 Free PMC article.

2

CX3CL1 intracellular domain and adult neurogenesis.

Benoit MR, Gayen M, Yan R. Benoit MR, et al. Aging (Albany NY). 2019 Nov 29;11(23):10783-10785. doi: 10.18632/aging.102504. Epub 2019 Nov 29. Aging (Albany NY). 2019. PMID: 31785144 Free PMC article. No abstract available.

3

Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs.

Yan R. Yan R. Transl Neurodegener. 2016 Jul 14;5:13. doi: 10.1186/s40035-016-0061-5. eCollection 2016. Transl Neurodegener. 2016. PMID: 27418961 Free PMC article. Review.

4

Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.

Hu X, Fan Q, Hou H, Yan R. Hu X, et al. J Neurochem. 2016 Jan;136(2):234-49. doi: 10.1111/jnc.13395. Epub 2015 Nov 13. J Neurochem. 2016. PMID: 26465092 Free PMC article. Review.

5

Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep-wake Disturbances in AD Mice.

Yao AY, Halloran PJ, Ge Y, Singh N, Zhou J, Galske J, He W, Yan R, Hu X. Yao AY, et al. J Neurosci. 2023 Aug 30;43(35):6197-6211. doi: 10.1523/JNEUROSCI.2124-22.2023. Epub 2023 Aug 3. J Neurosci. 2023. PMID: 37536983 Free PMC article.

6

Metabotropic Glutamate Receptors in Alzheimer's Disease Synaptic Dysfunction: Therapeutic Opportunities and Hope for the Future.

Srivastava A, Das B, Yao AY, Yan R. Srivastava A, et al. J Alzheimers Dis. 2020;78(4):1345-1361. doi: 10.3233/JAD-201146. J Alzheimers Dis. 2020. PMID: 33325389 Free PMC article. Review.

7

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.

Yan R, Fan Q, Zhou J, Vassar R. Yan R, et al. Neurosci Biobehav Rev. 2016 Jun;65:326-40. doi: 10.1016/j.neubiorev.2016.03.025. Epub 2016 Apr 1. Neurosci Biobehav Rev. 2016. PMID: 27044452 Free PMC article. Review.

8

A Close Look at BACE1 Inhibitors for Alzheimer's Disease Treatment.

Das B, Yan R. Das B, et al. CNS Drugs. 2019 Mar;33(3):251-263. doi: 10.1007/s40263-019-00613-7. CNS Drugs. 2019. PMID: 30830576 Free PMC article. Review.

9

BACE1 controls synaptic function through modulating release of synaptic vesicles.

Das B, Singh N, Yao AY, Zhou J, He W, Hu X, Yan R. Das B, et al. Mol Psychiatry. 2021 Nov;26(11):6394-6410. doi: 10.1038/s41380-021-01166-2. Epub 2021 Jun 22. Mol Psychiatry. 2021. PMID: 34158621 Free PMC article.

10

BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1.

Singh N, Benoit MR, Zhou J, Das B, Davila-Velderrain J, Kellis M, Tsai LH, Hu X, Yan R. Singh N, et al. Sci Adv. 2022 Jun 17;8(24):eabo1286. doi: 10.1126/sciadv.abo1286. Epub 2022 Jun 17. Sci Adv. 2022. PMID: 35714196 Free PMC article.

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