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VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction.
Blankenship HE, Carter KA, Cassidy NT, Markiewicz AN, Thellmann MI, Sharpe AL, Freeman WM, Beckstead MJ. Blankenship HE, et al. bioRxiv [Preprint]. 2023 Nov 17:2023.11.16.567486. doi: 10.1101/2023.11.16.567486. bioRxiv. 2023. Update in: Nat Commun. 2024 Nov 8;15(1):9673. doi: 10.1038/s41467-024-53891-1 PMID: 38014232 Free PMC article. Updated. Preprint.
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis.
Bhaskaran S, Kumar G, Thadathil N, Piekarz KM, Mohammed S, Lopez SD, Qaisar R, Walton D, Brown JL, Murphy A, Smith N, Saunders D, Beckstead MJ, Plafker S, Lewis TL Jr, Towner R, Deepa SS, Richardson A, Axtell RC, Van Remmen H. Bhaskaran S, et al. Redox Biol. 2023 Feb;59:102550. doi: 10.1016/j.redox.2022.102550. Epub 2022 Nov 26. Redox Biol. 2023. PMID: 36470129 Free PMC article.
15 results