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The smallpox vaccine induces an early neutralizing IgM response.
Moyron-Quiroz JE, McCausland MM, Kageyama R, Sette A, Crotty S. Moyron-Quiroz JE, et al. Vaccine. 2009 Dec 10;28(1):140-7. doi: 10.1016/j.vaccine.2009.09.086. Epub 2009 Oct 12. Vaccine. 2009. PMID: 19822230 Free PMC article.