R01 AI077595-04/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.

Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW. Basu U, et al. Cell. 2011 Feb 4;144(3):353-63. doi: 10.1016/j.cell.2011.01.001. Epub 2011 Jan 20. Cell. 2011. PMID: 21255825 Free PMC article.

Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining.

Eccleston J, Yan C, Yuan K, Alt FW, Selsing E. Eccleston J, et al. J Immunol. 2011 Feb 15;186(4):2336-43. doi: 10.4049/jimmunol.1003104. Epub 2011 Jan 17. J Immunol. 2011. PMID: 21242524 Free PMC article.

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