R01 AI161570/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2022	2
2023	2
2024	6
2025	1

1

PROTAC'ing oncoproteins: targeted protein degradation for cancer therapy.

Kelm JM, Pandey DS, Malin E, Kansou H, Arora S, Kumar R, Gavande NS. Kelm JM, et al. Mol Cancer. 2023 Mar 30;22(1):62. doi: 10.1186/s12943-022-01707-5. Mol Cancer. 2023. PMID: 36991452 Free PMC article. Review.

2

Development of robust antiviral assays using relevant apical-out human airway organoids.

Lee JH, LeCher JC, Parigoris E, Shinagawa N, Sentosa J, Manfredi C, Goh SL, De R, Tao S, Zandi K, Amblard F, Sorscher EJ, Spence JR, Tirouvanziam R, Schinazi RF, Takayama S. Lee JH, et al. bioRxiv [Preprint]. 2024 Jul 12:2024.01.02.573939. doi: 10.1101/2024.01.02.573939. bioRxiv. 2024. PMID: 38260306 Free PMC article. Preprint.

3

Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections.

Hurwitz SJ, De R, LeCher JC, Downs-Bowen JA, Goh SL, Zandi K, McBrayer T, Amblard F, Patel D, Kohler JJ, Bhasin M, Dobosh BS, Sukhatme V, Tirouvanziam RM, Schinazi RF. Hurwitz SJ, et al. Viruses. 2024 Apr 22;16(4):651. doi: 10.3390/v16040651. Viruses. 2024. PMID: 38675992 Free PMC article.

4

Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.

Amblard F, LeCher JC, De R, Zhou S, Liu P, Goh SL, Tao S, Patel D, Downs-Bowen J, Zandi K, Zhang H, Chaudhry G, McBrayer T, Muczynski M, Al-Homoudi A, Engel J, Lan S, Sarafianos SG, Kovari LC, Schinazi RF. Amblard F, et al. Eur J Med Chem. 2024 Mar 15;268:116263. doi: 10.1016/j.ejmech.2024.116263. Epub 2024 Feb 24. Eur J Med Chem. 2024. PMID: 38432056

5

Inactivation of SARS-CoV-2 and COVID-19 Patient Samples for Contemporary Immunology and Metabolomics Studies.

Eddins DJ, Bassit LC, Chandler JD, Haddad NS, Musall KL, Yang J, Kosters A, Dobosh BS, Hernández MR, Ramonell RP, Tirouvanziam RM, Lee FE, Zandi K, Schinazi RF, Ghosn EEB. Eddins DJ, et al. Immunohorizons. 2022 Feb 16;6(2):144-155. doi: 10.4049/immunohorizons.2200005. Immunohorizons. 2022. PMID: 35173021 Free PMC article.

6

Targeting the Epidermal Growth Factor Receptor with Molecular Degraders: State-of-the-Art and Future Opportunities.

Maity P, Chatterjee J, Patil KT, Arora S, Katiyar MK, Kumar M, Samarbakhsh A, Joshi G, Bhutani P, Chugh M, Gavande NS, Kumar R. Maity P, et al. J Med Chem. 2023 Mar 9;66(5):3135-3172. doi: 10.1021/acs.jmedchem.2c01242. Epub 2023 Feb 22. J Med Chem. 2023. PMID: 36812395 Review.

7

N4-Hydroxycytidine/molnupiravir inhibits RNA virus-induced encephalitis by producing less fit mutated viruses.

Ojha D, Hill CS, Zhou S, Evans A, Leung JM, Schneider CA, Amblard F, Woods TA, Schinazi RF, Baric RS, Peterson KE, Swanstrom R. Ojha D, et al. PLoS Pathog. 2024 Sep 30;20(9):e1012574. doi: 10.1371/journal.ppat.1012574. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39348391 Free PMC article.

8

Informatics and Computational Approaches for the Discovery and Optimization of Natural Product-Inspired Inhibitors of the SARS-CoV-2 2'-O-Methyltransferase.

Hanna GS, Benjamin MM, Choo YM, De R, Schinazi RF, Nielson SE, Hevel JM, Hamann MT. Hanna GS, et al. J Nat Prod. 2024 Feb 23;87(2):217-227. doi: 10.1021/acs.jnatprod.3c00875. Epub 2024 Jan 19. J Nat Prod. 2024. PMID: 38242544 Free PMC article.

9

Assessment of a Computational Approach to Predict Drug Resistance Mutations for HIV, HBV and SARS-CoV-2.

Patel D, Ono SK, Bassit L, Verma K, Amblard F, Schinazi RF. Patel D, et al. Molecules. 2022 Aug 24;27(17):5413. doi: 10.3390/molecules27175413. Molecules. 2022. PMID: 36080181 Free PMC article.

10

Enhanced safety and efficacy profile of CD40 antibody upon encapsulation in pHe-triggered membrane-adhesive nanoliposomes.

Althobaiti S, Parajuli P, Luong D, Sau S, Polin LA, Kim S, Ge Y, Iyer AK, Gavande NS. Althobaiti S, et al. Nanomedicine (Lond). 2025 Jan;20(2):155-166. doi: 10.1080/17435889.2024.2446008. Epub 2024 Dec 29. Nanomedicine (Lond). 2025. PMID: 39764733

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