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N-Demethylation is a major route of 2-amino-3-methylimidazo[4,5-f]quinoline metabolism in mouse.
Drug Metab Dispos. 2008 Jun;36(6):1143-52. doi: 10.1124/dmd.107.019166. Epub 2008 Mar 20.
Drug Metab Dispos. 2008.
PMID: 18356269
Free PMC article.
Activation of aminoimidazole carcinogens by nitrosation: mutagenicity and nucleotide adducts.
Zenser TV, Lakshmi VM, Schut HA, Zhou HJ, Josephy P.
Zenser TV, et al.
Mutat Res. 2009 Mar 17;673(2):109-15. doi: 10.1016/j.mrgentox.2008.12.007.
Mutat Res. 2009.
PMID: 19449459
Free PMC article.
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Stability and reactivity of 2-nitrosoamino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Lakshmi VM, Hsu FF, Schut HA, Zenser TV.
Lakshmi VM, et al.
Chem Res Toxicol. 2006 Feb;19(2):325-33. doi: 10.1021/tx050305x.
Chem Res Toxicol. 2006.
PMID: 16485910
Free PMC article.
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