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Resolvins suppress tumor growth and enhance cancer therapy.
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S, Panigrahy D. Sulciner ML, et al. J Exp Med. 2018 Jan 2;215(1):115-140. doi: 10.1084/jem.20170681. Epub 2017 Nov 30. J Exp Med. 2018. PMID: 29191914 Free PMC article.
Aspirin-triggered proresolving mediators stimulate resolution in cancer.
Gilligan MM, Gartung A, Sulciner ML, Norris PC, Sukhatme VP, Bielenberg DR, Huang S, Kieran MW, Serhan CN, Panigrahy D. Gilligan MM, et al. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6292-6297. doi: 10.1073/pnas.1804000116. Epub 2019 Mar 12. Proc Natl Acad Sci U S A. 2019. PMID: 30862734 Free PMC article.
Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases.
Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, Sukhatme V, Hammock BD, Kieran MW, Huang S, Bhasin M, Serhan CN, Sukhatme VP. Panigrahy D, et al. J Clin Invest. 2019 Jun 17;129(7):2964-2979. doi: 10.1172/JCI127282. eCollection 2019 Jun 17. J Clin Invest. 2019. PMID: 31205032 Free PMC article.