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Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Dar AA, Bezrookove V, Nosrati M, Ice R, Patino JM, Vaquero EM, Parrett B, Leong SP, Kim KB, Debs RJ, Soroceanu L, Miller JR 3rd, Desprez PY, Cleaver JE, Salomonis N, McAllister S, Kashani-Sabet M. Dar AA, et al. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206824119. doi: 10.1073/pnas.2206824119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969744 Free PMC article.
Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma.
Ursu S, Majid S, Garger C, de Semir D, Bezrookove V, Desprez PY, McAllister S, Soroceanu L, Nosrati M, Yimam K, Hassoun A, Osorio R, Kashani-Sabet M, Dar AA. Ursu S, et al. Oncogenesis. 2019 Aug 13;8(8):42. doi: 10.1038/s41389-019-0153-z. Oncogenesis. 2019. PMID: 31409772 Free PMC article.
PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex.
de Semir D, Bezrookove V, Nosrati M, Scanlon KR, Singer E, Judkins J, Rieken C, Wu C, Shen J, Schmudermayer C, Dar AA, Miller JR 3rd, Cobbs C, Yount G, Desprez PY, Debs RJ, Salomonis N, McAllister S, Cleaver JE, Soroceanu L, Kashani-Sabet M. de Semir D, et al. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):9064-9073. doi: 10.1073/pnas.1914505117. Epub 2020 Apr 9. Proc Natl Acad Sci U S A. 2020. PMID: 32273388 Free PMC article.
PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
de Semir D, Bezrookove V, Nosrati M, Dar AA, Wu C, Shen J, Rieken C, Venkatasubramanian M, Miller JR 3rd, Desprez PY, McAllister S, Soroceanu L, Debs RJ, Salomonis N, Schadendorf D, Cleaver JE, Kashani-Sabet M. de Semir D, et al. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5766-E5775. doi: 10.1073/pnas.1804779115. Epub 2018 Jun 4. Proc Natl Acad Sci U S A. 2018. PMID: 29866840 Free PMC article.
12 results