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RAC1 as a Therapeutic Target in Malignant Melanoma.
Cannon AC, Uribe-Alvarez C, Chernoff J. Cannon AC, et al. Trends Cancer. 2020 Jun;6(6):478-488. doi: 10.1016/j.trecan.2020.02.021. Epub 2020 Mar 18. Trends Cancer. 2020. PMID: 32460002 Free PMC article. Review.
Development and Utility of a PAK1-Selective Degrader.
Chow HY, Karchugina S, Groendyke BJ, Toenjes S, Hatcher J, Donovan KA, Fischer ES, Abalakov G, Faezov B, Dunbrack R, Gray NS, Chernoff J. Chow HY, et al. J Med Chem. 2022 Dec 8;65(23):15627-15641. doi: 10.1021/acs.jmedchem.2c00756. Epub 2022 Nov 23. J Med Chem. 2022. PMID: 36416208 Free PMC article.
Targeting effector pathways in RAC1P29S-driven malignant melanoma.
Uribe-Alvarez C, Guerrero-Rodríguez SL, Rhodes J, Cannon A, Chernoff J, Araiza-Olivera D. Uribe-Alvarez C, et al. Small GTPases. 2021 Jul;12(4):273-281. doi: 10.1080/21541248.2020.1728469. Epub 2020 Feb 17. Small GTPases. 2021. PMID: 32043900 Free PMC article.
A New Rho(d) Map to Diffuse Gastric Cancer.
Benton D, Chernoff J. Benton D, et al. Cancer Discov. 2020 Feb;10(2):182-184. doi: 10.1158/2159-8290.CD-19-1327. Cancer Discov. 2020. PMID: 32024682 Free PMC article.
Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
Cannon AC, Budagyan K, Uribe-Alvarez C, Kurimchak AM, Araiza-Olivera D, Cai KQ, Peri S, Zhou Y, Duncan JS, Chernoff J. Cannon AC, et al. bioRxiv [Preprint]. 2023 Jun 28:2023.06.27.546707. doi: 10.1101/2023.06.27.546707. bioRxiv. 2023. Update in: Oncogene. 2024 Mar;43(10):729-743. doi: 10.1038/s41388-024-02947-z PMID: 37425776 Free PMC article. Updated. Preprint.