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Current avenues of gene therapy in Pompe disease.
Leon-Astudillo C, Trivedi PD, Sun RC, Gentry MS, Fuller DD, Byrne BJ, Corti M. Leon-Astudillo C, et al. Curr Opin Neurol. 2023 Oct 1;36(5):464-473. doi: 10.1097/WCO.0000000000001187. Epub 2023 Jul 19. Curr Opin Neurol. 2023. PMID: 37639402 Free PMC article. Review.
Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.
Conroy LR, Clarke HA, Allison DB, Valenca SS, Sun Q, Hawkinson TR, Young LEA, Ferreira JE, Hammonds AV, Dunne JB, McDonald RJ, Absher KJ, Dong BE, Bruntz RC, Markussen KH, Juras JA, Alilain WJ, Liu J, Gentry MS, Angel PM, Waters CM, Sun RC. Conroy LR, et al. Nat Commun. 2023 May 13;14(1):2759. doi: 10.1038/s41467-023-38437-1. Nat Commun. 2023. PMID: 37179348 Free PMC article.
The multifaceted roles of the brain glycogen.
Markussen KH, Corti M, Byrne BJ, Vander Kooi CW, Sun RC, Gentry MS. Markussen KH, et al. J Neurochem. 2024 May;168(5):728-743. doi: 10.1111/jnc.15926. Epub 2023 Aug 9. J Neurochem. 2024. PMID: 37554056 Review.
In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues.
Young LEA, Conroy LR, Clarke HA, Hawkinson TR, Bolton KE, Sanders WC, Chang JE, Webb MB, Alilain WJ, Vander Kooi CW, Drake RR, Andres DA, Badgett TC, Wagner LM, Allison DB, Sun RC, Gentry MS. Young LEA, et al. EMBO Mol Med. 2022 Nov 8;14(11):e16029. doi: 10.15252/emmm.202216029. Epub 2022 Sep 5. EMBO Mol Med. 2022. PMID: 36059248 Free PMC article.
In situ microwave fixation provides an instantaneous snapshot of the brain metabolome.
Juras JA, Webb MB, Young LEA, Markussen KH, Hawkinson TR, Buoncristiani MD, Bolton KE, Coburn PT, Williams MI, Sun LPY, Sanders WC, Bruntz RC, Conroy LR, Wang C, Gentry MS, Smith BN, Sun RC. Juras JA, et al. Cell Rep Methods. 2023 Apr 18;3(4):100455. doi: 10.1016/j.crmeth.2023.100455. eCollection 2023 Apr 24. Cell Rep Methods. 2023. PMID: 37159672 Free PMC article.