Mechanisms of change in extended cognitive behavioral treatment for tobacco dependence

Drug Alcohol Depend. 2010 Jun 1;109(1-3):114-9. doi: 10.1016/j.drugalcdep.2009.12.021. Epub 2010 Jan 21.

Abstract

Aim: To evaluate potential mediators of an extended cognitive behavioral smoking cessation intervention.

Design: Analysis of data from a randomized clinical trial of smoking cessation.

Setting: The Habit Abatement Clinic, University of California, San Francisco.

Participants: Participants were older cigarette smokers (>/=50 years old). Those receiving Standard Treatment (N=100) were compared to those receiving extended cognitive behavioral treatment (N=99).

Measurements: Negative affect was measured with the Profile of Mood States (POMS), the Medical Outcome Studies 36-item Short-Form Health Survey (SF-36), and the Perceived Stress Scale (PSS). Abstinence-specific social support was measured with the Partner Interaction Questionnaire (PIQ). Motivation to quit and abstinence self-efficacy were measured on 1-10 scales with the Thoughts about Abstinence Questionnaire. All were measured at the beginning of treatment and week 52.

Results: Analyses revealed that extended CBT increased abstinence self-efficacy over the first 52 weeks postcessation. This effect, in turn, was positively associated with 7-day point prevalence abstinence at week 64 while controlling for treatment condition, and eliminated the independent effect of treatment condition on abstinence. The test of mediation indicated a significant effect, and abstinence self-efficacy accounted for 61% to 83% of the total effect of treatment condition on smoking abstinence. Results failed to support a mediational role of negative affect, abstinence-specific social support, or motivation to quit.

Conclusions: The results of the present study are consistent with theories of relapse and studies of more time-limited interventions, and underscore the importance of abstinence self-efficacy in achieving long-term abstinence from cigarettes.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Affect
  • Bupropion / therapeutic use
  • Chewing Gum
  • Cognitive Behavioral Therapy*
  • Dopamine Uptake Inhibitors / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motivation
  • Nicotine / administration & dosage
  • Nicotine / therapeutic use
  • Nicotinic Agonists / administration & dosage
  • Nicotinic Agonists / therapeutic use
  • Psychometrics
  • Secondary Prevention
  • Self Efficacy
  • Smoking Cessation / methods*
  • Social Support
  • Stress, Psychological / psychology
  • Tobacco Use Disorder / psychology
  • Tobacco Use Disorder / therapy*
  • Treatment Outcome

Substances

  • Chewing Gum
  • Dopamine Uptake Inhibitors
  • Nicotinic Agonists
  • Bupropion
  • Nicotine