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Page 1
HRI stress signaling and HbF production.
Chen JJ. Chen JJ. Blood. 2020 Jun 11;135(24):2113-2114. doi: 10.1182/blood.2020006300. Blood. 2020. PMID: 32526022 Free PMC article.
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation.
Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, Wu X, Gehrke L, Rice CM, An X, Christou HA, Mohandas N, Carr SA, Chen JJ, Orkin SH, Lander ES, Sankaran VG. Basak A, et al. Nat Genet. 2020 Feb;52(2):138-145. doi: 10.1038/s41588-019-0568-7. Epub 2020 Jan 20. Nat Genet. 2020. PMID: 31959994 Free PMC article.
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.
Abdel-Nour M, Carneiro LAM, Downey J, Tsalikis J, Outlioua A, Prescott D, Da Costa LS, Hovingh ES, Farahvash A, Gaudet RG, Molinaro R, van Dalen R, Lau CCY, Azimi FC, Escalante NK, Trotman-Grant A, Lee JE, Gray-Owen SD, Divangahi M, Chen JJ, Philpott DJ, Arnoult D, Girardin SE. Abdel-Nour M, et al. Science. 2019 Jul 5;365(6448):eaaw4144. doi: 10.1126/science.aaw4144. Science. 2019. PMID: 31273097 Free PMC article.
Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia.
Matte A, Federti E, Winter M, Koerner A, Harmeier A, Mazer N, Tomka T, Di Paolo ML, De Falco L, Andolfo I, Beneduce E, Iolascon A, Macias-Garcia A, Chen JJ, Janin A, Lebouef C, Turrini F, Brugnara C, De Franceschi L. Matte A, et al. JCI Insight. 2019 Nov 14;4(22):e130111. doi: 10.1172/jci.insight.130111. JCI Insight. 2019. PMID: 31593554 Free PMC article.
ATF4 Regulates CD4+ T Cell Immune Responses through Metabolic Reprogramming.
Yang X, Xia R, Yue C, Zhai W, Du W, Yang Q, Cao H, Chen X, Obando D, Zhu Y, Chen X, Chen JJ, Piganelli J, Wipf P, Jiang Y, Xiao G, Wu C, Jiang J, Lu B. Yang X, et al. Cell Rep. 2018 May 8;23(6):1754-1766. doi: 10.1016/j.celrep.2018.04.032. Cell Rep. 2018. PMID: 29742431 Free PMC article.
18 results