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Nox2 is a mediator of chronic CsA nephrotoxicity.
Djamali A, Reese S, Hafez O, Vidyasagar A, Jacobson L, Swain W, Kolehmainen C, Huang L, Wilson NA, Torrealba JR. Djamali A, et al. Am J Transplant. 2012 Aug;12(8):1997-2007. doi: 10.1111/j.1600-6143.2012.04081.x. Epub 2012 May 8. Am J Transplant. 2012. PMID: 22568654 Free PMC article.
Increased C4d in post-reperfusion biopsies and increased donor specific antibodies at one-week post transplant are risk factors for acute rejection in mild to moderately sensitized kidney transplant recipients.
Djamali A, Muth BL, Ellis TM, Mohamed M, Fernandez LA, Miller KM, Bellingham JM, Odorico JS, Mezrich JD, Pirsch JD, D'Alessandro TM, Vidyasagar V, Hofmann RM, Torrealba JR, Kaufman DB, Foley DP. Djamali A, et al. Kidney Int. 2013 Jun;83(6):1185-92. doi: 10.1038/ki.2013.44. Epub 2013 Feb 27. Kidney Int. 2013. PMID: 23447068 Free PMC article.