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Growing knowledge of the mTOR signaling network.
Huang K, Fingar DC. Huang K, et al. Semin Cell Dev Biol. 2014 Dec;36:79-90. doi: 10.1016/j.semcdb.2014.09.011. Epub 2014 Sep 19. Semin Cell Dev Biol. 2014. PMID: 25242279 Free PMC article. Review.
mTORC1 and mTORC2 expression in inner retinal neurons and glial cells.
Losiewicz MK, Elghazi L, Fingar DC, Rajala RVS, Lentz SI, Fort PE, Abcouwer SF, Gardner TW. Losiewicz MK, et al. Exp Eye Res. 2020 Aug;197:108131. doi: 10.1016/j.exer.2020.108131. Epub 2020 Jul 2. Exp Eye Res. 2020. PMID: 32622801 Free PMC article.
AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.
Kazyken D, Magnuson B, Bodur C, Acosta-Jaquez HA, Zhang D, Tong X, Barnes TM, Steinl GK, Patterson NE, Altheim CH, Sharma N, Inoki K, Cartee GD, Bridges D, Yin L, Riddle SM, Fingar DC. Kazyken D, et al. Sci Signal. 2019 Jun 11;12(585):eaav3249. doi: 10.1126/scisignal.aav3249. Sci Signal. 2019. PMID: 31186373 Free PMC article.