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GDF15 Induces Anorexia through Nausea and Emesis.
Borner T, Shaulson ED, Ghidewon MY, Barnett AB, Horn CC, Doyle RP, Grill HJ, Hayes MR, De Jonghe BC. Borner T, et al. Cell Metab. 2020 Feb 4;31(2):351-362.e5. doi: 10.1016/j.cmet.2019.12.004. Epub 2020 Jan 9. Cell Metab. 2020. PMID: 31928886 Free PMC article.
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects.
Asker M, Krieger JP, Liles A, Tinsley IC, Borner T, Maric I, Doebley S, Furst CD, Börchers S, Longo F, Bhat YR, De Jonghe BC, Hayes MR, Doyle RP, Skibicka KP. Asker M, et al. Diabetes Obes Metab. 2023 Mar;25(3):856-877. doi: 10.1111/dom.14937. Epub 2023 Jan 9. Diabetes Obes Metab. 2023. PMID: 36495318 Free PMC article.
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