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Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation.
Toxicol Appl Pharmacol. 2010 Nov 15;249(1):101-6. doi: 10.1016/j.taap.2010.09.003. Epub 2010 Sep 16.
Toxicol Appl Pharmacol. 2010.
PMID: 20840855
Free PMC article.
Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic.
Hough LB, Nalwalk JW, Yang J, Conroy JL, VanAlstine MA, Yang W, Gargano J, Shan Z, Zhang SZ, Wentland MP, Phillips JG, Knapp BI, Bidlack JM, Zuiderveld OP, Leurs R, Ding X.
Hough LB, et al.
Pain. 2011 Apr;152(4):878-887. doi: 10.1016/j.pain.2011.01.001.
Pain. 2011.
PMID: 21316152
Free PMC article.
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