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Page 1
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Hulce KR, Jaishankar P, Lee GM, Bohn MF, Connelly EJ, Wucherer K, Ongpipattanakul C, Volk RF, Chuo SW, Arkin MR, Renslo AR, Craik CS. Hulce KR, et al. Cell Chem Biol. 2022 May 19;29(5):785-798.e19. doi: 10.1016/j.chembiol.2022.03.007. Epub 2022 Mar 31. Cell Chem Biol. 2022. PMID: 35364007 Free PMC article.
Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA. Guo CJ, et al. Cell. 2017 Jan 26;168(3):517-526.e18. doi: 10.1016/j.cell.2016.12.021. Epub 2017 Jan 19. Cell. 2017. PMID: 28111075 Free PMC article.
Global identification of peptidase specificity by multiplex substrate profiling.
O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS. O'Donoghue AJ, et al. Nat Methods. 2012 Nov;9(11):1095-100. doi: 10.1038/nmeth.2182. Epub 2012 Sep 30. Nat Methods. 2012. PMID: 23023596 Free PMC article.
19 results