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2018 1
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39 results

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Page 1
Inflammasome activation in infected macrophages drives COVID-19 pathology.
Sefik E, Qu R, Junqueira C, Kaffe E, Mirza H, Zhao J, Brewer JR, Han A, Steach HR, Israelow B, Blackburn HN, Velazquez SE, Chen YG, Halene S, Iwasaki A, Meffre E, Nussenzweig M, Lieberman J, Wilen CB, Kluger Y, Flavell RA. Sefik E, et al. Nature. 2022 Jun;606(7914):585-593. doi: 10.1038/s41586-022-04802-1. Epub 2022 Apr 28. Nature. 2022. PMID: 35483404 Free PMC article.
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Jarret A, Jackson R, Duizer C, Healy ME, Zhao J, Rone JM, Bielecki P, Sefik E, Roulis M, Rice T, Sivanathan KN, Zhou T, Solis AG, Honcharova-Biletska H, Vélez K, Hartner S, Low JS, Qu R, de Zoete MR, Palm NW, Ring AM, Weber A, Moor AE, Kluger Y, Nowarski R, Flavell RA. Jarret A, et al. Cell. 2020 Jan 9;180(1):50-63.e12. doi: 10.1016/j.cell.2019.12.016. Cell. 2020. PMID: 31923399 Free PMC article.
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche.
Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA. Roulis M, et al. Nature. 2020 Apr;580(7804):524-529. doi: 10.1038/s41586-020-2166-3. Epub 2020 Apr 1. Nature. 2020. PMID: 32322056 Free PMC article.
Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial.
Goldberg SB, Schalper KA, Gettinger SN, Mahajan A, Herbst RS, Chiang AC, Lilenbaum R, Wilson FH, Omay SB, Yu JB, Jilaveanu L, Tran T, Pavlik K, Rowen E, Gerrish H, Komlo A, Gupta R, Wyatt H, Ribeiro M, Kluger Y, Zhou G, Wei W, Chiang VL, Kluger HM. Goldberg SB, et al. Lancet Oncol. 2020 May;21(5):655-663. doi: 10.1016/S1470-2045(20)30111-X. Epub 2020 Apr 3. Lancet Oncol. 2020. PMID: 32251621 Free PMC article. Clinical Trial.
Gene trajectory inference for single-cell data by optimal transport metrics.
Qu R, Cheng X, Sefik E, Stanley Iii JS, Landa B, Strino F, Platt S, Garritano J, Odell ID, Coifman R, Flavell RA, Myung P, Kluger Y. Qu R, et al. Nat Biotechnol. 2024 Apr 5:10.1038/s41587-024-02186-3. doi: 10.1038/s41587-024-02186-3. Online ahead of print. Nat Biotechnol. 2024. PMID: 38580861
Zero-preserving imputation of single-cell RNA-seq data.
Linderman GC, Zhao J, Roulis M, Bielecki P, Flavell RA, Nadler B, Kluger Y. Linderman GC, et al. Nat Commun. 2022 Jan 11;13(1):192. doi: 10.1038/s41467-021-27729-z. Nat Commun. 2022. PMID: 35017482 Free PMC article.
Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3.
Yuan Q, Basit A, Liang W, Qu R, Luan Y, Ren C, Li A, Xu X, Liu X, Yang C, Kuo A, Pierce R, Zhang L, Turk B, Hu X, Li F, Cui W, Li R, Huang D, Mo L, Sessa WC, Lee PJ, Kluger Y, Su B, Tang W, He J, Wu D. Yuan Q, et al. Sci Transl Med. 2021 Apr 28;13(591):eabc2499. doi: 10.1126/scitranslmed.abc2499. Sci Transl Med. 2021. PMID: 33910977 Free PMC article.
The Spectral Underpinning of word2vec.
Jaffe A, Kluger Y, Lindenbaum O, Patsenker J, Peterfreund E, Steinerberger S. Jaffe A, et al. Front Appl Math Stat. 2020 Dec;6:593406. doi: 10.3389/fams.2020.593406. Epub 2020 Dec 3. Front Appl Math Stat. 2020. PMID: 34504892 Free PMC article.
39 results