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Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus.
Gaussin V, Morley GE, Cox L, Zwijsen A, Vance KM, Emile L, Tian Y, Liu J, Hong C, Myers D, Conway SJ, Depre C, Mishina Y, Behringer RR, Hanks MC, Schneider MD, Huylebroeck D, Fishman GI, Burch JB, Vatner SF. Gaussin V, et al. Circ Res. 2005 Aug 5;97(3):219-26. doi: 10.1161/01.RES.0000177862.85474.63. Epub 2005 Jul 21. Circ Res. 2005. PMID: 16037571 Free PMC article.