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Myeloperoxidase produces nitrating oxidants in vivo.
Gaut JP, Byun J, Tran HD, Lauber WM, Carroll JA, Hotchkiss RS, Belaaouaj A, Heinecke JW. Gaut JP, et al. J Clin Invest. 2002 May;109(10):1311-9. doi: 10.1172/JCI15021. J Clin Invest. 2002. PMID: 12021246 Free PMC article.
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Bergt C, Pennathur S, Fu X, Byun J, O'Brien K, McDonald TO, Singh P, Anantharamaiah GM, Chait A, Brunzell J, Geary RL, Oram JF, Heinecke JW. Bergt C, et al. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13032-7. doi: 10.1073/pnas.0405292101. Epub 2004 Aug 23. Proc Natl Acad Sci U S A. 2004. PMID: 15326314 Free PMC article.