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Anticoagulant heparan sulfate to not clot--or not?
Shworak NW, Kobayashi T, de Agostini A, Smits NC. Shworak NW, et al. Prog Mol Biol Transl Sci. 2010;93:153-78. doi: 10.1016/S1877-1173(10)93008-1. Prog Mol Biol Transl Sci. 2010. PMID: 20807645 Review.
The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease.
Smits NC, Kurup S, Rops AL, ten Dam GB, Massuger LF, Hafmans T, Turnbull JE, Spillmann D, Li JP, Kennel SJ, Wall JS, Shworak NW, Dekhuijzen PN, van der Vlag J, van Kuppevelt TH. Smits NC, et al. J Biol Chem. 2010 Dec 24;285(52):41143-51. doi: 10.1074/jbc.M110.153791. Epub 2010 Sep 13. J Biol Chem. 2010. PMID: 20837479 Free PMC article.
The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition.
Stan RV, Tse D, Deharvengt SJ, Smits NC, Xu Y, Luciano MR, McGarry CL, Buitendijk M, Nemani KV, Elgueta R, Kobayashi T, Shipman SL, Moodie KL, Daghlian CP, Ernst PA, Lee HK, Suriawinata AA, Schned AR, Longnecker DS, Fiering SN, Noelle RJ, Gimi B, Shworak NW, Carrière C. Stan RV, et al. Dev Cell. 2012 Dec 11;23(6):1203-18. doi: 10.1016/j.devcel.2012.11.003. Dev Cell. 2012. PMID: 23237953 Free PMC article.