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Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy.
J Mol Cell Cardiol. 2011 Mar;50(3):460-70. doi: 10.1016/j.yjmcc.2010.11.012. Epub 2010 Nov 25.
J Mol Cell Cardiol. 2011.
PMID: 21111744
Free PMC article.
Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.
Tang M, Zhang X, Li Y, Guan Y, Ai X, Szeto C, Nakayama H, Zhang H, Ge S, Molkentin JD, Houser SR, Chen X.
Tang M, et al.
Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H519-28. doi: 10.1152/ajpheart.00265.2010. Epub 2010 Jun 11.
Am J Physiol Heart Circ Physiol. 2010.
PMID: 20543081
Free PMC article.
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Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Raake PW, Zhang X, Vinge LE, Brinks H, Gao E, Jaleel N, Li Y, Tang M, Most P, Dorn GW 2nd, Houser SR, Katus HA, Chen X, Koch WJ.
Raake PW, et al.
Circulation. 2012 May 1;125(17):2108-18. doi: 10.1161/CIRCULATIONAHA.111.044255. Epub 2012 Apr 10.
Circulation. 2012.
PMID: 22496128
Free PMC article.
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