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Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias.
Yajima T, Murofushi Y, Zhou H, Park S, Housman J, Zhong ZH, Nakamura M, Machida M, Hwang KK, Gu Y, Dalton ND, Yajima T, Yasukawa H, Peterson KL, Knowlton KU. Yajima T, et al. Circulation. 2011 Dec 13;124(24):2690-701. doi: 10.1161/CIRCULATIONAHA.111.028498. Epub 2011 Nov 14. Circulation. 2011. PMID: 22082679 Free PMC article.