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Long non-coding RNA and chromatin remodeling.
Han P, Chang CP. Han P, et al. RNA Biol. 2015;12(10):1094-8. doi: 10.1080/15476286.2015.1063770. Epub 2015 Jul 15. RNA Biol. 2015. PMID: 26177256 Free PMC article. Review.
Epigenetic and lncRNA regulation of cardiac pathophysiology.
Chang CP, Han P. Chang CP, et al. Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1767-71. doi: 10.1016/j.bbamcr.2016.03.005. Epub 2016 Mar 9. Biochim Biophys Acta. 2016. PMID: 26969820 Free PMC article. Review.
Myheart hits the core of chromatin.
Han P, Chang CP. Han P, et al. Cell Cycle. 2015;14(6):787-8. doi: 10.1080/15384101.2015.1010963. Cell Cycle. 2015. PMID: 25668574 Free PMC article. No abstract available.
Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment.
Yang J, Savvatis K, Kang JS, Fan P, Zhong H, Schwartz K, Barry V, Mikels-Vigdal A, Karpinski S, Kornyeyev D, Adamkewicz J, Feng X, Zhou Q, Shang C, Kumar P, Phan D, Kasner M, López B, Diez J, Wright KC, Kovacs RL, Chen PS, Quertermous T, Smith V, Yao L, Tschöpe C, Chang CP. Yang J, et al. Nat Commun. 2016 Dec 14;7:13710. doi: 10.1038/ncomms13710. Nat Commun. 2016. PMID: 27966531 Free PMC article.
A long noncoding RNA protects the heart from pathological hypertrophy.
Han P, Li W, Lin CH, Yang J, Shang C, Nuernberg ST, Jin KK, Xu W, Lin CY, Lin CJ, Xiong Y, Chien H, Zhou B, Ashley E, Bernstein D, Chen PS, Chen HV, Quertermous T, Chang CP. Han P, et al. Nature. 2014 Oct 2;514(7520):102-106. doi: 10.1038/nature13596. Epub 2014 Aug 10. Nature. 2014. PMID: 25119045 Free PMC article.
Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.
Han P, Li W, Yang J, Shang C, Lin CH, Cheng W, Hang CT, Cheng HL, Chen CH, Wong J, Xiong Y, Zhao M, Drakos SG, Ghetti A, Li DY, Bernstein D, Chen HS, Quertermous T, Chang CP. Han P, et al. Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1772-81. doi: 10.1016/j.bbamcr.2016.03.002. Epub 2016 Mar 4. Biochim Biophys Acta. 2016. PMID: 26952936 Free PMC article.
Inappropriate p53 activation during development induces features of CHARGE syndrome.
Van Nostrand JL, Brady CA, Jung H, Fuentes DR, Kozak MM, Johnson TM, Lin CY, Lin CJ, Swiderski DL, Vogel H, Bernstein JA, Attié-Bitach T, Chang CP, Wysocka J, Martin DM, Attardi LD. Van Nostrand JL, et al. Nature. 2014 Oct 9;514(7521):228-32. doi: 10.1038/nature13585. Epub 2014 Aug 3. Nature. 2014. PMID: 25119037 Free PMC article.