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Page 1
Structure and dynamics of GPCR signaling complexes.
Hilger D, Masureel M, Kobilka BK. Hilger D, et al. Nat Struct Mol Biol. 2018 Jan;25(1):4-12. doi: 10.1038/s41594-017-0011-7. Epub 2018 Jan 8. Nat Struct Mol Biol. 2018. PMID: 29323277 Free PMC article. Review.
Negative allosteric modulation of the glucagon receptor by RAMP2.
Krishna Kumar K, O'Brien ES, Habrian CH, Latorraca NR, Wang H, Tuneew I, Montabana E, Marqusee S, Hilger D, Isacoff EY, Mathiesen JM, Kobilka BK. Krishna Kumar K, et al. Cell. 2023 Mar 30;186(7):1465-1477.e18. doi: 10.1016/j.cell.2023.02.028. Cell. 2023. PMID: 37001505 Free PMC article.
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Rasmussen SG, et al. Nature. 2011 Jul 19;477(7366):549-55. doi: 10.1038/nature10361. Nature. 2011. PMID: 21772288 Free PMC article.
Time-resolved cryo-EM of G protein activation by a GPCR.
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, Gao Y, Eskici G, Seven AB, Panova O, Hilger D, Casiraghi M, He F, Maul L, Gmeiner P, Kobilka BK, Hildebrand PW, Skiniotis G. Papasergi-Scott MM, et al. bioRxiv [Preprint]. 2023 Mar 21:2023.03.20.533387. doi: 10.1101/2023.03.20.533387. bioRxiv. 2023. Update in: Nature. 2024 May;629(8014):1182-1191. doi: 10.1038/s41586-024-07153-1 PMID: 36993214 Free PMC article. Updated. Preprint.
Step-wise activation of a Family C GPCR.
Kumar KK, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Kumar KK, et al. bioRxiv [Preprint]. 2023 Aug 30:2023.08.29.555158. doi: 10.1101/2023.08.29.555158. bioRxiv. 2023. PMID: 37693614 Free PMC article. Preprint.
95 results