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Conditional knockout of TOG results in CNS hypomyelination.
Maggipinto MJ, Ford J, Le KH, Tutolo JW, Furusho M, Wizeman JW, Bansal R, Barbarese E. Maggipinto MJ, et al. Glia. 2017 Mar;65(3):489-501. doi: 10.1002/glia.23106. Epub 2017 Jan 7. Glia. 2017. PMID: 28063167 Free PMC article.
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway.
Verrier JD, Jackson TC, Bansal R, Kochanek PM, Puccio AM, Okonkwo DO, Jackson EK. Verrier JD, et al. J Neurochem. 2012 Jul;122(1):115-25. doi: 10.1111/j.1471-4159.2012.07705.x. Epub 2012 Mar 20. J Neurochem. 2012. PMID: 22360621 Free PMC article.
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