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Lower levels of Th1 and Th2 cytokines in cerebrospinal fluid (CSF) at the time of initial CSF shunt placement in children are associated with subsequent shunt revision surgeries.
Simon TD, Sedano S, Rosenberg-Hasson Y, Durazo-Arvizu R, Whitlock KB, Hodor P, Hauptman JS, Limbrick DD, McDonald P, Ojemann JG, Maecker HT; Cerebrospinal FLuId MicroBiota in Shunts CLIMB Study Group. Simon TD, et al. Cytokine. 2023 Sep;169:156310. doi: 10.1016/j.cyto.2023.156310. Epub 2023 Jul 29. Cytokine. 2023. PMID: 37523803 Free PMC article.
Characterization of cerebrospinal fluid (CSF) microbiota at the time of initial surgical intervention for children with hydrocephalus.
Pandey S, Whitlock KB, Test MR, Hodor P, Pope CE, Limbrick DD Jr, McDonald PJ, Hauptman JS, Hoffman LR, Simon TD; Cerebrospinal FLuId MicroBiota in Shunts (CLIMB) Study Group. Pandey S, et al. PLoS One. 2023 Jun 21;18(6):e0280682. doi: 10.1371/journal.pone.0280682. eCollection 2023. PLoS One. 2023. PMID: 37342995 Free PMC article.
Molecular Characterization of Microbiota in Cerebrospinal Fluid From Patients With CSF Shunt Infections Using Whole Genome Amplification Followed by Shotgun Sequencing.
Hodor P, Pope CE, Whitlock KB, Hoffman LR, Limbrick DL, McDonald PJ, Hauptman JS, Ojemann JG, Simon TD. Hodor P, et al. Front Cell Infect Microbiol. 2021 Aug 20;11:699506. doi: 10.3389/fcimb.2021.699506. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34490140 Free PMC article.
Characterization of cerebrospinal fluid (CSF) microbiota from patients with CSF shunt infection and reinfection using high throughput sequencing of 16S ribosomal RNAgenes.
Whitlock KB, Pope CE, Hodor P, Hoffman LR, Limbrick DL Jr, McDonald PJ, Hauptman JS, Ojemann JG, Simon TD; Cerebrospinal FLuId MicroBiota in Shunts Study (CLIMB) Group. Whitlock KB, et al. PLoS One. 2021 Jan 6;16(1):e0244643. doi: 10.1371/journal.pone.0244643. eCollection 2021. PLoS One. 2021. PMID: 33406142 Free PMC article.