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Step-wise activation of a Family C GPCR.
Kumar KK, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Kumar KK, et al. bioRxiv [Preprint]. 2023 Aug 30:2023.08.29.555158. doi: 10.1101/2023.08.29.555158. bioRxiv. 2023. PMID: 37693614 Free PMC article. Preprint.
Ciliary localization of a light-activated neuronal GPCR shapes behavior.
Winans AM, Friedmann D, Stanley C, Xiao T, Liu TL, Chang CJ, Isacoff EY. Winans AM, et al. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2311131120. doi: 10.1073/pnas.2311131120. Epub 2023 Oct 16. Proc Natl Acad Sci U S A. 2023. PMID: 37844228 Free PMC article.
Subtype-specific conformational landscape of NMDA receptor gating.
Bleier J, Furtado de Mendonca PR, Habrian CH, Stanley C, Vyklicky V, Isacoff EY. Bleier J, et al. Cell Rep. 2024 Aug 27;43(8):114634. doi: 10.1016/j.celrep.2024.114634. Epub 2024 Aug 17. Cell Rep. 2024. PMID: 39154344 Free PMC article.
Domain coupling in activation of a family C GPCR.
Latorraca NR, Sabaat S, Habrian C, Bleier J, Stanley C, Marqusee S, Isacoff EY. Latorraca NR, et al. bioRxiv [Preprint]. 2024 Feb 29:2024.02.28.582567. doi: 10.1101/2024.02.28.582567. bioRxiv. 2024. PMID: 38464305 Free PMC article. Preprint.
Development of covalent chemogenetic K2P channel activators.
Deal PE, Lee H, Mondal A, Lolicato M, Mendonça PRF, Black H, Jang S, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL Jr. Deal PE, et al. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. doi: 10.1016/j.chembiol.2024.06.006. Cell Chem Biol. 2024. PMID: 39029456
11 results