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Stress-vs-time signals allow the prediction of structurally catastrophic events during fracturing of immature cartilage and predetermine the biomechanical, biochemical, and structural impairment.
J Struct Biol. 2013 Sep;183(3):501-511. doi: 10.1016/j.jsb.2013.06.011. Epub 2013 Jun 28.
J Struct Biol. 2013.
PMID: 23810923
Free PMC article.
IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage.
Wheeler CA, Jafarzadeh SR, Rocke DM, Grodzinsky AJ.
Wheeler CA, et al.
Osteoarthritis Cartilage. 2009 Jul;17(7):944-52. doi: 10.1016/j.joca.2009.02.001. Epub 2009 Feb 15.
Osteoarthritis Cartilage. 2009.
PMID: 19250984
Free PMC article.
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Distinct horizontal patterns in the spatial organization of superficial zone chondrocytes of human joints.
Rolauffs B, Williams JM, Grodzinsky AJ, Kuettner KE, Cole AA.
Rolauffs B, et al.
J Struct Biol. 2008 May;162(2):335-44. doi: 10.1016/j.jsb.2008.01.010. Epub 2008 Feb 2.
J Struct Biol. 2008.
PMID: 18325787
Free PMC article.
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