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Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor.
Am J Physiol Cell Physiol. 2007 Feb;292(2):C850-6. doi: 10.1152/ajpcell.00356.2006. Epub 2006 Sep 27.
Am J Physiol Cell Physiol. 2007.
PMID: 17005604
Free article.
High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function.
Chronopoulos A, Tang A, Beglova E, Trackman PC, Roy S.
Chronopoulos A, et al.
Diabetes. 2010 Dec;59(12):3159-66. doi: 10.2337/db10-0365. Epub 2010 Sep 7.
Diabetes. 2010.
PMID: 20823103
Free PMC article.
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Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation.
Iftikhar M, Hurtado P, Bais MV, Wigner N, Stephens DN, Gerstenfeld LC, Trackman PC.
Iftikhar M, et al.
J Biol Chem. 2011 Jan 14;286(2):909-18. doi: 10.1074/jbc.M110.155622. Epub 2010 Nov 11.
J Biol Chem. 2011.
PMID: 21071451
Free PMC article.
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