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Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure.
De Jonghe BC, Hayes MR, Banno R, Skibicka KP, Zimmer DJ, Bowen KA, Leichner TM, Alhadeff AL, Kanoski SE, Cyr NE, Nillni EA, Grill HJ, Bence KK. De Jonghe BC, et al. Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1002-11. doi: 10.1152/ajpendo.00639.2010. Epub 2011 Mar 15. Am J Physiol Endocrinol Metab. 2011. PMID: 21406615 Free PMC article.