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Synthetic triterpenoids have cytotoxicity in pediatric acute lymphoblastic leukemia cell lines but cytotoxicity is independent of induced ceramide increase in MOLT-4 cells.
Leukemia. 2008 Jun;22(6):1258-62. doi: 10.1038/sj.leu.2405023. Epub 2007 Nov 22.
Leukemia. 2008.
PMID: 18033322
No abstract available.
Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.
Lapillonne H, Konopleva M, Tsao T, Gold D, McQueen T, Sutherland RL, Madden T, Andreeff M.
Lapillonne H, et al.
Cancer Res. 2003 Sep 15;63(18):5926-39.
Cancer Res. 2003.
PMID: 14522919
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