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Further studies on the application of vinylogous amides and β-halovinylaldehydes to the regiospecific synthesis of unsymmetrical, polyfunctionalized 2,3,4- and 1,2,3,4- substituted pyrroles.
Gupton JT, Shimozono A, Crawford E, Ortolani J, Clark E, Mahoney M, Heese C, Noble J, Mandry CP, Kanters R, Dominey RN, Goldman EW, Sikorski JA, Fisher DC. Gupton JT, et al. Tetrahedron. 2018 May 24;74(21):2650-2663. doi: 10.1016/j.tet.2018.04.017. Epub 2018 Apr 7. Tetrahedron. 2018. PMID: 30344350 Free PMC article.
Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities.
Gupton JT, Yeudall S, Telang N, Hoerrner M, Huff E, Crawford E, Lounsbury K, Kimmel M, Curry W, Harrison A, Juekun W, Shimozono A, Ortolani J, Lescalleet K, Patteson J, Moore-Stoll V, Rohena CC, Mooberry SL, Obaidullah AJ, Kellogg GE, Sikorski JA. Gupton JT, et al. Bioorg Med Chem. 2017 Jun 15;25(12):3206-3214. doi: 10.1016/j.bmc.2017.04.012. Epub 2017 Apr 11. Bioorg Med Chem. 2017. PMID: 28433513 Free PMC article.
Application of vinylogous carbamates and vinylogous aminonitriles to the regiospecific synthesis of uniquely functionalized pyrroles and quinolones.
Gupton JT, Crawford E, Mahoney M, Clark E, Curry W, Lane A, Shimozono A, Moore-Stoll V, Elofson K, Juekun W, Newton M, Yeudall S, Jaekle E, Kanters R, Sikorski JA. Gupton JT, et al. Tetrahedron. 2018 Dec 27;74(52):7408-7420. doi: 10.1016/j.tet.2018.10.078. Epub 2018 Nov 5. Tetrahedron. 2018. PMID: 31289413 Free PMC article.
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