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Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms.
J Biol Chem. 2018 Nov 9;293(45):17336-17348. doi: 10.1074/jbc.RA118.005316. Epub 2018 Sep 21.
J Biol Chem. 2018.
PMID: 30242125
Free PMC article.
Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein at the Single-Molecule Level.
Manger LH, Foote AK, Wood SL, Holden MR, Heylman KD, Margittai M, Goldsmith RH.
Manger LH, et al.
Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15584-15588. doi: 10.1002/anie.201708242. Epub 2017 Nov 14.
Angew Chem Int Ed Engl. 2017.
PMID: 29063723
Free PMC article.
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Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation.
Foote AK , Manger LH , Holden MR , Margittai M , Goldsmith RH .
Foote AK , et al.
Phys Chem Chem Phys. 2019 Jan 23;21(4):1863-1871. doi: 10.1039/c8cp06971a.
Phys Chem Chem Phys. 2019.
PMID: 30632561
Free PMC article.
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