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Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice.
Yadav-Samudrala BJ, Dodson H, Ramineni S, Kim E, Poklis JL, Lu D, Ignatowska-Jankowska BM, Lichtman AH, Fitting S. Yadav-Samudrala BJ, et al. PLoS One. 2024 Jun 24;19(6):e0305868. doi: 10.1371/journal.pone.0305868. eCollection 2024. PLoS One. 2024. PMID: 38913661 Free PMC article.
Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms.
Xu C, Yadav-Samudrala BJ, Xu C, Nath B, Mistry T, Jiang W, Niphakis MJ, Cravatt BF, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Xu C, et al. Cells. 2022 Mar 2;11(5):857. doi: 10.3390/cells11050857. Cells. 2022. PMID: 35269478 Free PMC article.
Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids.
Hermes DJ, Jacobs IR, Key MC, League AF, Yadav-Samudrala BJ, Xu C, McLane VD, Nass SR, Jiang W, Meeker RB, Ignatowska-Jankowska BM, Lichtman AH, Li Z, Wu Z, Yuan H, Knapp PE, Hauser KF, Fitting S. Hermes DJ, et al. J Neuroinflammation. 2020 Nov 18;17(1):345. doi: 10.1186/s12974-020-01971-6. J Neuroinflammation. 2020. PMID: 33208151 Free PMC article.
Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat.
League AF, Gorman BL, Hermes DJ, Johnson CT, Jacobs IR, Yadav-Samudrala BJ, Poklis JL, Niphakis MJ, Cravatt BF, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. League AF, et al. Front Neurol. 2021 Aug 16;12:651272. doi: 10.3389/fneur.2021.651272. eCollection 2021. Front Neurol. 2021. PMID: 34484091 Free PMC article.
12 results