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ANGPTL3 targeting: The power of versatile lipid-lowering.
Pessentheiner AR, Ramms B, Gordts PLSM. Pessentheiner AR, et al. Atherosclerosis. 2018 Jan;268:185-187. doi: 10.1016/j.atherosclerosis.2017.10.002. Epub 2017 Oct 6. Atherosclerosis. 2018. PMID: 29111225 Free PMC article. No abstract available.
The human milk oligosaccharide 3'sialyllactose reduces low-grade inflammation and atherosclerosis development in mice.
Pessentheiner AR, Spann NJ, Autran CA, Oh TG, Grunddal KV, Coker JK, Painter CD, Ramms B, Chiang AW, Wang CY, Hsiao J, Wang Y, Quach A, Booshehri LM, Hammond A, Tognaccini C, Latasiewicz J, Willemsen L, Zengler K, de Winther MP, Hoffman HM, Philpott M, Cribbs AP, Oppermann U, Lewis NE, Witztum JL, Yu R, Atkins AR, Downes M, Evans RM, Glass CK, Bode L, Gordts PL. Pessentheiner AR, et al. JCI Insight. 2024 Nov 8;9(21):e181329. doi: 10.1172/jci.insight.181329. JCI Insight. 2024. PMID: 39325548 Free PMC article.
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis.
Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. Weiss RJ, et al. Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9311-9317. doi: 10.1073/pnas.1920880117. Epub 2020 Apr 10. Proc Natl Acad Sci U S A. 2020. PMID: 32277030 Free PMC article.