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CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice.
Dash PK, Chen C, Kaminski R, Su H, Mancuso P, Sillman B, Zhang C, Liao S, Sravanam S, Liu H, Waight E, Guo L, Mathews S, Sariyer R, Mosley RL, Poluektova LY, Caocci M, Amini S, Gorantla S, Burdo TH, Edagwa B, Gendelman HE, Khalili K. Dash PK, et al. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2217887120. doi: 10.1073/pnas.2217887120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126704 Free PMC article.
Impaired extinction of cocaine seeking in HIV-infected mice is accompanied by peripheral and central immune dysregulation.
Barker J, Buck L, Xie Q, Willis M, Side C, Giacometti L, Gaskill P, Park K, Shaheen F, Guo L, Gorantla S. Barker J, et al. Res Sq [Preprint]. 2023 Sep 28:rs.3.rs-3276379. doi: 10.21203/rs.3.rs-3276379/v1. Res Sq. 2023. Update in: Commun Biol. 2024 Mar 30;7(1):387. doi: 10.1038/s42003-024-06079-8 PMID: 37841842 Free PMC article. Updated. Preprint.