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Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA.
Dmytrenko O, Neumann GC, Hallmark T, Keiser DJ, Crowley VM, Vialetto E, Mougiakos I, Wandera KG, Domgaard H, Weber J, Gaudin T, Metcalf J, Gray BN, Begemann MB, Jackson RN, Beisel CL. Dmytrenko O, et al. Nature. 2023 Jan;613(7944):588-594. doi: 10.1038/s41586-022-05559-3. Epub 2023 Jan 4. Nature. 2023. PMID: 36599979 Free PMC article.
Structure of a type IV CRISPR-Cas ribonucleoprotein complex.
Zhou Y, Bravo JPK, Taylor HN, Steens JA, Jackson RN, Staals RHJ, Taylor DW. Zhou Y, et al. iScience. 2021 Feb 17;24(3):102201. doi: 10.1016/j.isci.2021.102201. eCollection 2021 Mar 19. iScience. 2021. PMID: 33733066 Free PMC article.