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Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.
Khalil B, Chhangani D, Wren MC, Smith CL, Lee JH, Li X, Puttinger C, Tsai CW, Fortin G, Morderer D, Gao J, Liu F, Lim CK, Chen J, Chou CC, Croft CL, Gleixner AM, Donnelly CJ, Golde TE, Petrucelli L, Oskarsson B, Dickson DW, Zhang K, Shorter J, Yoshimura SH, Barmada SJ, Rincon-Limas DE, Rossoll W. Khalil B, et al. Mol Neurodegener. 2022 Dec 8;17(1):80. doi: 10.1186/s13024-022-00585-1. Mol Neurodegener. 2022. PMID: 36482422 Free PMC article.
TDP-43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP-43 Proteinopathies.
Pickles SR, Gonzalez Bejarano J, Narayan A, Daughrity L, Maroto Cidfuentes C, Reeves MM, Yue M, Castellanos Otero P, Estades Ayuso V, Dunmore J, Song Y, Tong J, DeTure M, Rawlinson B, Castanedes-Casey M, Dulski J, Cerquera-Cleves C, Zhang Y, Josephs KA, Dickson DW, Petrucelli L, Wszolek ZK, Prudencio M. Pickles SR, et al. Mov Disord. 2025 Jan 9. doi: 10.1002/mds.30104. Online ahead of print. Mov Disord. 2025. PMID: 39788898