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Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity.
Proc Natl Acad Sci U S A. 2010 May 25;107(21):9730-5. doi: 10.1073/pnas.1002575107. Epub 2010 May 11.
Proc Natl Acad Sci U S A. 2010.
PMID: 20460307
Free PMC article.
Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity.
Lee SJ, Hwang AB, Kenyon C.
Lee SJ, et al.
Curr Biol. 2010 Dec 7;20(23):2131-6. doi: 10.1016/j.cub.2010.10.057. Epub 2010 Nov 18.
Curr Biol. 2010.
PMID: 21093262
Free PMC article.
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Widespread protein aggregation as an inherent part of aging in C. elegans.
David DC, Ollikainen N, Trinidad JC, Cary MP, Burlingame AL, Kenyon C.
David DC, et al.
PLoS Biol. 2010 Aug 10;8(8):e1000450. doi: 10.1371/journal.pbio.1000450.
PLoS Biol. 2010.
PMID: 20711477
Free PMC article.
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