R37AI027690/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Advantages of crystallographic fragment screening: functional and mechanistic insights from a powerful platform for efficient drug discovery.

Patel D, Bauman JD, Arnold E. Patel D, et al. Prog Biophys Mol Biol. 2014 Nov-Dec;116(2-3):92-100. doi: 10.1016/j.pbiomolbio.2014.08.004. Epub 2014 Aug 10. Prog Biophys Mol Biol. 2014. PMID: 25117499 Free PMC article. Review.

Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage.

Das K, Martinez SE, Bandwar RP, Arnold E. Das K, et al. Nucleic Acids Res. 2014 Jul;42(12):8125-37. doi: 10.1093/nar/gku487. Epub 2014 May 31. Nucleic Acids Res. 2014. PMID: 24880687 Free PMC article.

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