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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2019 | 1 |
2020 | 1 |
2021 | 2 |
2022 | 3 |
2024 | 0 |
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6 results
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Page 1
Knowledge-based approaches to drug discovery for rare diseases.
Drug Discov Today. 2022 Feb;27(2):490-502. doi: 10.1016/j.drudis.2021.10.014. Epub 2021 Oct 27.
Drug Discov Today. 2022.
PMID: 34718207
Free PMC article.
Review.
Advancing the Research and Development of Enzyme Replacement Therapies for Lysosomal Storage Diseases.
Puhl AC, Ekins S.
Puhl AC, et al.
GEN Biotechnol. 2022 Apr;1(2):156-162. doi: 10.1089/genbio.2021.0013. Epub 2022 Apr 20.
GEN Biotechnol. 2022.
PMID: 35706761
Free PMC article.
Item in Clipboard
Using Bibliometric Analysis and Machine Learning to Identify Compounds Binding to Sialidase-1.
Klein JJ, Baker NC, Foil DH, Zorn KM, Urbina F, Puhl AC, Ekins S.
Klein JJ, et al.
ACS Omega. 2021 Jan 20;6(4):3186-3193. doi: 10.1021/acsomega.0c05591. eCollection 2021 Feb 2.
ACS Omega. 2021.
PMID: 33553934
Free PMC article.
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Exploiting machine learning for end-to-end drug discovery and development.
Ekins S, Puhl AC, Zorn KM, Lane TR, Russo DP, Klein JJ, Hickey AJ, Clark AM.
Ekins S, et al.
Nat Mater. 2019 May;18(5):435-441. doi: 10.1038/s41563-019-0338-z. Epub 2019 Apr 18.
Nat Mater. 2019.
PMID: 31000803
Free PMC article.
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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.
Nelvagal HR, Eaton SL, Wang SH, Eultgen EM, Takahashi K, Le SQ, Nesbitt R, Dearborn JT, Siano N, Puhl AC, Dickson PI, Thompson G, Murdoch F, Brennan PM, Gray M, Greenhalgh SN, Tennant P, Gregson R, Clutton E, Nixon J, Proudfoot C, Guido S, Lillico SG, Whitelaw CBA, Lu JY, Hofmann SL, Ekins S, Sands MS, Wishart TM, Cooper JD.
Nelvagal HR, et al.
J Clin Invest. 2022 Oct 17;132(20):e163107. doi: 10.1172/JCI163107.
J Clin Invest. 2022.
PMID: 36040802
Free PMC article.
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Repurposing the Dihydropyridine Calcium Channel Inhibitor Nicardipine as a Nav1.8 Inhibitor In Vivo for Pitt Hopkins Syndrome.
Ekins S, Puhl AC, Davidow A.
Ekins S, et al.
Pharm Res. 2020 Jun 11;37(7):127. doi: 10.1007/s11095-020-02853-5.
Pharm Res. 2020.
PMID: 32529312
Free PMC article.
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