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The CD3 zeta subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse.
J Immunol. 2011 Jun 15;186(12):6839-47. doi: 10.4049/jimmunol.1002721. Epub 2011 May 4.
J Immunol. 2011.
PMID: 21543646
Free PMC article.
Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifs.
Becker AM, Blevins JS, Tomson FL, Eitson JL, Medeiros JJ, Yarovinsky F, Norgard MV, van Oers NS.
Becker AM, et al.
J Immunol. 2010 Jun 15;184(12):6822-32. doi: 10.4049/jimmunol.0902058. Epub 2010 May 14.
J Immunol. 2010.
PMID: 20483726
Free PMC article.
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The cytoplasmic tail of the T cell receptor CD3 epsilon subunit contains a phospholipid-binding motif that regulates T cell functions.
Deford-Watts LM, Tassin TC, Becker AM, Medeiros JJ, Albanesi JP, Love PE, Wülfing C, van Oers NS.
Deford-Watts LM, et al.
J Immunol. 2009 Jul 15;183(2):1055-64. doi: 10.4049/jimmunol.0900404. Epub 2009 Jun 19.
J Immunol. 2009.
PMID: 19542373
Free PMC article.
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