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A single-cell atlas of the normal and malformed human brain vasculature.
Winkler EA, Kim CN, Ross JM, Garcia JH, Gil E, Oh I, Chen LQ, Wu D, Catapano JS, Raygor K, Narsinh K, Kim H, Weinsheimer S, Cooke DL, Walcott BP, Lawton MT, Gupta N, Zlokovic BV, Chang EF, Abla AA, Lim DA, Nowakowski TJ. Winkler EA, et al. Science. 2022 Mar 4;375(6584):eabi7377. doi: 10.1126/science.abi7377. Epub 2022 Mar 4. Science. 2022. PMID: 35084939 Free PMC article.
Type-I-interferon-responsive microglia shape cortical development and behavior.
Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Barron JJ, Wade SD, Cuevas B, Vainchtein ID, Silva NJ, Guajardo R, Xiao Y, Lidsky PV, Wang EY, Rivera BM, Taloma SE, Kim DK, Kaminskaya E, Nakao-Inoue H, Schwer B, Arnold TD, Molofsky AB, Condello C, Andino R, Nowakowski TJ, Molofsky AV. Escoubas CC, et al. Cell. 2024 Apr 11;187(8):1936-1954.e24. doi: 10.1016/j.cell.2024.02.020. Epub 2024 Mar 14. Cell. 2024. PMID: 38490196 Free article.
Single-cell epigenomics reveals mechanisms of human cortical development.
Ziffra RS, Kim CN, Ross JM, Wilfert A, Turner TN, Haeussler M, Casella AM, Przytycki PF, Keough KC, Shin D, Bogdanoff D, Kreimer A, Pollard KS, Ament SA, Eichler EE, Ahituv N, Nowakowski TJ. Ziffra RS, et al. Nature. 2021 Oct;598(7879):205-213. doi: 10.1038/s41586-021-03209-8. Epub 2021 Oct 6. Nature. 2021. PMID: 34616060 Free PMC article.
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids.
Popova G, Soliman SS, Kim CN, Keefe MG, Hennick KM, Jain S, Li T, Tejera D, Shin D, Chhun BB, McGinnis CS, Speir M, Gartner ZJ, Mehta SB, Haeussler M, Hengen KB, Ransohoff RR, Piao X, Nowakowski TJ. Popova G, et al. Cell Stem Cell. 2021 Dec 2;28(12):2153-2166.e6. doi: 10.1016/j.stem.2021.08.015. Epub 2021 Sep 17. Cell Stem Cell. 2021. PMID: 34536354 Free PMC article.
Type I interferon responsive microglia shape cortical development and behavior.
Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Cuevas B, Vainchtein ID, Silva NJ, Xiao Y, Lidsky PV, Wang EY, Taloma SE, Nakao-Inoue H, Schwer B, Andino R, Nowakowski TJ, Molofsky AV. Escoubas CC, et al. bioRxiv [Preprint]. 2023 Mar 20:2021.04.29.441889. doi: 10.1101/2021.04.29.441889. bioRxiv. 2023. Update in: Cell. 2024 Apr 11;187(8):1936-1954.e24. doi: 10.1016/j.cell.2024.02.020 PMID: 35233577 Free PMC article. Updated. Preprint.
Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders.
Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, Cadwell CR, Bhaduri A, Popova G, Bearden CE, Pollen AA, Jacquemont S, Sanders SJ, Haussler D, Wiita AP, Frost NA, Sohal VS, Nowakowski TJ. Shin D, et al. Cell Stem Cell. 2024 Mar 7;31(3):421-432.e8. doi: 10.1016/j.stem.2024.01.010. Epub 2024 Feb 20. Cell Stem Cell. 2024. PMID: 38382530
Nests of dividing neuroblasts sustain interneuron production for the developing human brain.
Paredes MF, Mora C, Flores-Ramirez Q, Cebrian-Silla A, Del Dosso A, Larimer P, Chen J, Kang G, Gonzalez Granero S, Garcia E, Chu J, Delgado R, Cotter JA, Tang V, Spatazza J, Obernier K, Ferrer Lozano J, Vento M, Scott J, Studholme C, Nowakowski TJ, Kriegstein AR, Oldham MC, Hasenstaub A, Garcia-Verdugo JM, Alvarez-Buylla A, Huang EJ. Paredes MF, et al. Science. 2022 Jan 28;375(6579):eabk2346. doi: 10.1126/science.abk2346. Epub 2022 Jan 28. Science. 2022. PMID: 35084970 Free PMC article.
Single-cell delineation of lineage and genetic identity in the mouse brain.
Bandler RC, Vitali I, Delgado RN, Ho MC, Dvoretskova E, Ibarra Molinas JS, Frazel PW, Mohammadkhani M, Machold R, Maedler S, Liddelow SA, Nowakowski TJ, Fishell G, Mayer C. Bandler RC, et al. Nature. 2022 Jan;601(7893):404-409. doi: 10.1038/s41586-021-04237-0. Epub 2021 Dec 15. Nature. 2022. PMID: 34912118 Free PMC article.
16 results