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2020 12
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Page 1
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination.
Wimmers F, Donato M, Kuo A, Ashuach T, Gupta S, Li C, Dvorak M, Foecke MH, Chang SE, Hagan T, De Jong SE, Maecker HT, van der Most R, Cheung P, Cortese M, Bosinger SE, Davis M, Rouphael N, Subramaniam S, Yosef N, Utz PJ, Khatri P, Pulendran B. Wimmers F, et al. Cell. 2021 Jul 22;184(15):3915-3935.e21. doi: 10.1016/j.cell.2021.05.039. Epub 2021 Jun 25. Cell. 2021. PMID: 34174187 Free PMC article. Clinical Trial.
Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth.
Wimmers F, Burrell AR, Feng Y, Zheng H, Arunachalam PS, Hu M, Spranger S, Nyhoff LE, Joshi D, Trisal M, Awasthi M, Bellusci L, Ashraf U, Kowli S, Konvinse KC, Yang E, Blanco M, Pellegrini K, Tharp G, Hagan T, Chinthrajah RS, Nguyen TT, Grifoni A, Sette A, Nadeau KC, Haslam DB, Bosinger SE, Wrammert J, Maecker HT, Utz PJ, Wang TT, Khurana S, Khatri P, Staat MA, Pulendran B. Wimmers F, et al. Cell. 2023 Oct 12;186(21):4632-4651.e23. doi: 10.1016/j.cell.2023.08.044. Epub 2023 Sep 29. Cell. 2023. PMID: 37776858 Free PMC article.
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells.
Codarri Deak L, Nicolini V, Hashimoto M, Karagianni M, Schwalie PC, Lauener L, Varypataki EM, Richard M, Bommer E, Sam J, Joller S, Perro M, Cremasco F, Kunz L, Yanguez E, Hüsser T, Schlenker R, Mariani M, Tosevski V, Herter S, Bacac M, Waldhauer I, Colombetti S, Gueripel X, Wullschleger S, Tichet M, Hanahan D, Kissick HT, Leclair S, Freimoser-Grundschober A, Seeber S, Teichgräber V, Ahmed R, Klein C, Umaña P. Codarri Deak L, et al. Nature. 2022 Oct;610(7930):161-172. doi: 10.1038/s41586-022-05192-0. Epub 2022 Sep 28. Nature. 2022. PMID: 36171284 Free PMC article.
Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
Arunachalam PS, Scott MKD, Hagan T, Li C, Feng Y, Wimmers F, Grigoryan L, Trisal M, Edara VV, Lai L, Chang SE, Feng A, Dhingra S, Shah M, Lee AS, Chinthrajah S, Sindher SB, Mallajosyula V, Gao F, Sigal N, Kowli S, Gupta S, Pellegrini K, Tharp G, Maysel-Auslender S, Hamilton S, Aoued H, Hrusovsky K, Roskey M, Bosinger SE, Maecker HT, Boyd SD, Davis MM, Utz PJ, Suthar MS, Khatri P, Nadeau KC, Pulendran B. Arunachalam PS, et al. Nature. 2021 Aug;596(7872):410-416. doi: 10.1038/s41586-021-03791-x. Epub 2021 Jul 12. Nature. 2021. PMID: 34252919 Free PMC article.
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.
Prokhnevska N, Cardenas MA, Valanparambil RM, Sobierajska E, Barwick BG, Jansen C, Reyes Moon A, Gregorova P, delBalzo L, Greenwald R, Bilen MA, Alemozaffar M, Joshi S, Cimmino C, Larsen C, Master V, Sanda M, Kissick H. Prokhnevska N, et al. Immunity. 2023 Jan 10;56(1):107-124.e5. doi: 10.1016/j.immuni.2022.12.002. Epub 2022 Dec 28. Immunity. 2023. PMID: 36580918 Free PMC article.
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans.
Arunachalam PS, Wimmers F, Mok CKP, Perera RAPM, Scott M, Hagan T, Sigal N, Feng Y, Bristow L, Tak-Yin Tsang O, Wagh D, Coller J, Pellegrini KL, Kazmin D, Alaaeddine G, Leung WS, Chan JMC, Chik TSH, Choi CYC, Huerta C, Paine McCullough M, Lv H, Anderson E, Edupuganti S, Upadhyay AA, Bosinger SE, Maecker HT, Khatri P, Rouphael N, Peiris M, Pulendran B. Arunachalam PS, et al. Science. 2020 Sep 4;369(6508):1210-1220. doi: 10.1126/science.abc6261. Epub 2020 Aug 11. Science. 2020. PMID: 32788292 Free PMC article.
SREBP signaling is essential for effective B cell responses.
Luo W, Adamska JZ, Li C, Verma R, Liu Q, Hagan T, Wimmers F, Gupta S, Feng Y, Jiang W, Zhou J, Valore E, Wang Y, Trisal M, Subramaniam S, Osborne TF, Pulendran B. Luo W, et al. Nat Immunol. 2023 Feb;24(2):337-348. doi: 10.1038/s41590-022-01376-y. Epub 2022 Dec 28. Nat Immunol. 2023. PMID: 36577930 Free PMC article.
Mpox infection protects against re-challenge in rhesus macaques.
Aid M, Sciacca M, McMahan K, Hope D, Liu J, Jacob-Dolan C, Powers O, Barrett J, Wu C, Mutoni A, Murdza T, Richter H, Velasco J, Teow E, Boursiquot M, Cook A, Orekov T, Hamilton M, Pessaint L, Ryan A, Hayes T, Martinot AJ, Seaman MS, Lewis MG, Andersen H, Barouch DH. Aid M, et al. Cell. 2023 Oct 12;186(21):4652-4661.e13. doi: 10.1016/j.cell.2023.08.023. Epub 2023 Sep 20. Cell. 2023. PMID: 37734373 Free PMC article.
Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement.
Woodworth MH, Conrad RE, Haldopoulos M, Pouch SM, Babiker A, Mehta AK, Sitchenko KL, Wang CH, Strudwick A, Ingersoll JM, Philippe C, Lohsen S, Kocaman K, Lindner BG, Hatt JK, Jones RM, Miller C, Neish AS, Friedman-Moraco R, Karadkhele G, Liu KH, Jones DP, Mehta CC, Ziegler TR, Weiss DS, Larsen CP, Konstantinidis KT, Kraft CS. Woodworth MH, et al. Sci Transl Med. 2023 Nov;15(720):eabo2750. doi: 10.1126/scitranslmed.abo2750. Epub 2023 Nov 1. Sci Transl Med. 2023. PMID: 37910603 Free PMC article. Clinical Trial.
58 results