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HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.
Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S. Cui M, et al. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306454120. doi: 10.1073/pnas.2306454120. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170752 Free PMC article.
β cell acetate production and release are negligible.
Xu K, Nnyamah C, Pandya N, Sweis N, Corona-Avila I, Priyadarshini M, Wicksteed B, Layden BT. Xu K, et al. Islets. 2024 Dec 31;16(1):2339558. doi: 10.1080/19382014.2024.2339558. Epub 2024 Apr 12. Islets. 2024. PMID: 38607959 Free PMC article.
Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.
Sapao P, Roberson EDO, Shi B, Assassi S, Skaug B, Lee F, Naba A, Perez White BE, Córdova-Fletes C, Tsou PS, Sawalha AH, Gudjonsson JE, Ma F, Verma P, Bhattacharyya D, Carns M, Strauss JF 3rd, Sicard D, Tschumperlin DJ, Champer MI, Campagnola PJ, Teves ME, Varga J. Sapao P, et al. J Invest Dermatol. 2023 Feb;143(2):284-293. doi: 10.1016/j.jid.2022.08.052. Epub 2022 Sep 15. J Invest Dermatol. 2023. PMID: 36116512 Free PMC article.
24 results